under the microscope

Mouse Alzheimer’s reversed in new study.

Mouse Alzheimer’s reversed in new study. “Remarkably, not only did preserving NAD+ balance protect mice from developing AD, but delayed treatment in mice with advanced disease also enabled the brain to fix the major pathological events driven by the disease-causing […]

under the microscope

Peanut allergy treatment progress.

Peanut allergy treatment progress. “The median tolerated dose increased from 30 mg (equivalent to approximately 1/8th of a peanut) to 3000 mg (12 peanuts) at the exit challenge, representing a 100-fold increase.” This phase II trial shows promising results for peanut oral […]

under the microscope

The evolution of bacteria.

The evolution of bacteria. “The longest-running and most celebrated of modern evolution experiments is the appropriately named Long-Term Evolution Experiment (LTEE). Started by Richard Lenski in 1988 at the University of California, Irvine, and continuing in the hands of Jeffrey […]

under the microscope

The power of surrogate endpoints.

The power of surrogate endpoints. “Surrogate endpoints: measurable intermediate biological signals that reliably predict clinical benefit, such as biomarkers or imaging readouts.” By utilizing these proxies, clinical trials can be significantly expedited, decreasing costs and increasing efficiency in drug development. […]

under the microscope

The power of urolithin A.

The power of urolithin A. “This study is that critical first step and shows that urolithin A can safely enhance immune function in humans,” says Dr. Dominic Denk. Found in foods like pomegranates and walnuts, this compound rejuvenates immune cells, […]

under the microscope

This frog knows its face.

This frog knows its face. I’ve shared before about the discovery that tiny electrical fields help cells determine where a nose should be, for example. I can’t get enough of how cool this is. “Picasso tadpoles make largely normal frog […]

under the microscope

Algae as asphalt’s green hero.

Algae as asphalt’s green hero. “Algae-derived compounds can improve moisture resistance, flexibility and self-healing behavior in asphalt, potentially extending pavement life and reducing maintenance costs,” says Assoc. Prof. Elham Fini. ~ learn more

under the microscope

Plants’ secret language revealed.

Plants’ secret language revealed. Scientists have unraveled a century-old mystery of how plants communicate stress. “We are trying to build a foundational knowledge of understanding how communication in plants happens,” explains Vesna Bacheva. The study shows plants use negative pressure […]