Recent advances in Alzheimer’s disease. “In this review, we summarize the most recent updates in AD research on pathologic disease mechanisms and therapeutic strategies, highlighting advancements in apolipoprotein E (APOE) biology, neuroimmunology, biomarker discovery, and initial experience with new disease-modifying […]
CRISPR as a suicide pill for cancer cells. “In bacteria, this CRISPR acts as a suicide pill, intentionally killing a cell that has been infected by a virus to prevent its spread.” Researchers reengineered that idea so once a cell […]
A frog gut microbe for attacking tumors. “A single intravenous dose of Ewingella americana led to complete tumor elimination in 100% of treated animals, with no recurrence upon re-exposure to cancer cells.” It’s a preclinical mouse colorectal cancer result, but […]
Exhale longer, take more risks. “Prolonged exhalation increased risky choices by enhancing reward sensitivity and elevating cardiac parasympathetic activity.” The authors show that a longer exhale shifts autonomic state toward parasympathetic dominance and that shift tracks stronger reward responses in […]
A dividing cell from non-living parts. “It’s a big step forward to this holy grail of making a living thing out of dead components.” Researchers packed lab-made biomolecules into a membrane, then watched the synthetic cell grow, copy DNA, and […]
Guy in garage lab testing a new Alzheimer’s drug. “I designed and synthesized PAC-832 in a chemistry lab I built in my garage.” Douglas Yao walks through PAC-832, “the world’s first selective GalR1 antagonist,” plus why targeting galanin signaling might […]
What if humans could regrow tissue? “[The genes are] already there — you just need to learn how to get them to behave the way you want.” Texas A&M researchers used a two-step sequence of growth factors to regrow mice […]
The cancer Alzheimer’s disease paradox. “paradoxically, the risk of AD in patients with cancer is reduced by 25–35%. Conversely, the risk of cancer in patients with AD is halved.” ~ learn more
This specially-designed jacket pulls drinking water from thin air. “The textile incorporated into the jacket collects moisture and funnels it to detachable harvesting units. Those units are placed in a foldable collector piece and heated to produce water. The jacket […]
Manufacturing requirements are killing cell and gene therapy. Ruxandra Teslo argues that for CAR-T, paperwork-level thresholds and noisy tests can block drugs that still work, and turn manufacturing into the real bottleneck. “Legend Biotech’s leadership later calculated that if those […]