under the microscope

One-shot gene editing for LDL.

One-shot gene editing for LDL. “One dose of VERVE-102 led to dose-dependent, substantial, and sustained reductions in PCSK9 and LDL cholesterol levels.” It is a phase 1 study in 35 people, with LDL reductions up to 62% at the highest […]

under the microscope

Functional human sperm in a lab.

Functional human sperm in a lab. “Growing functional human sperm entirely outside the body.” Little by little we’re living in an era where humans are taking control over biology. In this example, they were able to coax stem cells into […]

under the microscope

Rods that run cone software.

Rods that run cone software. Despite my comment above about humanity taking control over biology, it’s also true that we still know very little about biology. “For more than 150 years, vertebrate vision has been understood as a two-part system: […]

under the microscope

Plants weaponize caffeine.

Plants weaponize caffeine. The chemical serves as a natural pesticide that “disturb[s] the behavior and growth of numerous insects and their larvae,” which helps explain why plants make it in the first place. In tests, some pests became uncoordinated and […]

under the microscope

Biology is a burrito.

Biology is a burrito. “But a cell looks more like a burrito,” says Michael Elowitz. The essay makes the case that cells are absurdly crowded, and you need numbers to really feel how fast and chaotic the inside of a […]

under the microscope

A way to rejuvenate the immune system.

A way to rejuvenate the immune system. Stimulating the liver to produce some of the signals of the thymus can reverse age-related declines in T-cell populations and enhance response to vaccination, which is evidence of boosted immune reaction. ~ learn […]

under the microscope

How exercise can lower Alzheimer’s risk.

How exercise can lower Alzheimer’s risk. “Now, closely examining cells from geriatric animals’ blood-brain barriers, the researchers noticed that a damaging protein, known as TNAP, proliferated on the surface of those cells in far greater numbers than on cells from […]