“This blood test clearly identifies Alzheimer’s tau tangles [aka, neurofibrillary tangles], which is our best biomarker measure of Alzheimer’s symptoms and dementia,” said co-senior author Randall J. Bateman, MD, professor of neurology at WashU Medicine in the WashU news release.” […]
“This blood test clearly identifies Alzheimer’s tau tangles [aka, neurofibrillary tangles], which is our best biomarker measure of Alzheimer’s symptoms and dementia,” said co-senior author Randall J. Bateman, MD, professor of neurology at WashU Medicine in the WashU news release.” […]
I had to look up this type of trial, where researchers use a large dataset to put together a hypothetical trial to try and glean causality from correlations. “Semaglutide was associated with 40% to 70% reduced risks of first-time [Alzheimer’s] […]
I had to look up this type of trial, where researchers use a large dataset to put together a hypothetical trial to try and glean causality from correlations. “Semaglutide was associated with 40% to 70% reduced risks of first-time [Alzheimer’s] […]
“Once again, human gut microbiota are being linked to the progression of a chronic ailment. Using artificial intelligence (AI), researchers at the Cleveland Clinic Lerner Research Institute found that “metabolites produced by bacteria in the gut” may influence the course […]
“Asceneuron’s lead drug candidate ASN51 is a small molecule designed to block OGA, an enzyme that plays a role in protein aggregation. By preventing tau aggregation, the drug is intended to slow Alzheimer’s progression. In Phase 1 tests in healthy […]
“After 20 weeks, what we found for the first time in a randomized controlled trial is that an intensive lifestyle intervention, without drugs, significantly improved cognition and function in many patients who had mild cognitive impairment or early-stage AD.” … […]
A win for machine learning algorithms. The article does quote a critic who says this is not yet good enough to be a legit test. “The proteins were able to predict all-cause dementia as well as particular types, including Alzheimer’s […]
There’s a protein that’s found in the kidney and brain that’s cleverly called KIBRA. “Kauwe, Pareja-Navarro et al. identify a KIBRA-dependent mechanism to repair the plasticity at synapses that is dysregulated in neurons underlying the loss of memory in tauopathy.” […]
Interesting research from the University of Toronto, which has a strong legacy and brand in this field. In ironic and stark contrast to the critical take linked above. “In yet another surprise attribute of the new class of obesity drugs, […]