tech, startups, internet

Proof of X

“At their core, social networks are primarily about one thing: Building social capital through signaling.” This post is much more interesting than the title suggests. Starting with Strava (fitness social network) as proof-of-physical-activity leads to many thought-provoking ideas of Strava […]

tech, startups, internet

Understanding biotech investing

“As with startups, biotech companies have high failure rates: 90% of clinical programs fail to receive FDA approval, while 92% of biotech companies are unprofitable at any given time.” | learn more

tech, startups, internet

The Moby Dick theory of big companies

This is a 2007 essay from Marc Andreessen. “The most important thing you need to know going into any discussion or interaction with a big company is that you’re Captain Ahab, and the big company is Moby Dick.” | learn more

tech, startups, internet

Quibi is shutting down after just 6 months

In 2018 this startup raised $1 billion at inception. It caused Steve Blank to ask Is the lean startup dead? Then we saw the fat startup’s launch teaser in January of this year. Here, the story ends, as “the first high-profile casualty of […]

tech, startups, internet

What working at Stripe has been like

“I joined Stripe four years ago to make starting an Internet business easier, mostly by work on Stripe Atlas. This has been a series of adjustments for me: to working as an employee, to experiencing hypergrowth, to being closer to […]

tech, startups, internet

The bull case for Opendoor

I’ve been casually following Opendoor since they were just a tiny startup buying and selling houses in Arizona. Now they’re about to go public via a SPAC at a $4.8 billion valuation. Here’s the bull case for “the Amazon of […]

tech, startups, internet

16 open problems in engineering biology

From team a16z bio: “As our engineering toolkit in bio expands to be more powerful than ever before, and the infrastructure to deliver, produce, and scale these solutions comes increasingly online, a whole new world of problems in biology begin […]