under the microscope

A protein to restore memories lost to Alzheimer’s.

There’s a protein that’s found in the kidney and brain that’s cleverly called KIBRA. “Kauwe, Pareja-Navarro et al. identify a KIBRA-dependent mechanism to repair the plasticity at synapses that is dysregulated in neurons underlying the loss of memory in tauopathy.” […]

under the microscope

Scientists see hope for curing autoimmune disease.

In autoimmune diseases, the body attacks its own cells. That poses a problem because stopping the attack also comes with lowering the body’s immunities against foreign invaders. Some recent understanding of cellular function, supported by clinical trial results, is promising. […]

retail therapy

The future 100: 2024 edition.

“Be future-ready and dive into 100 micro trends spanning culture creativity and connection. Join us as we take you on a journey into tomorrow’s world; a world where in the face of a bewildering amount of new technology, people are […]

better doing

Your calendar doesn’t lie.

“In short, he [Marcus Aurelius] was like a lot of us who claim that our family comes first, that there’s no one more important to us…but then we promptly put so many other things before them. Sometimes that stuff is […]

better doing

Just keep coming back.

This is about tennis, and also about more than tennis. “The key to successful tennis is to just keep coming back to the moment, no matter what! You cannot think about the mistake you just made or worry about the […]

tech, startups, internet

A quant winter’s tale.

This might include the best explanation of factor investing I’ve seen yet. “If you throw a rock anywhere in AQR’s surprisingly dowdy headquarters in Greenwich, chances are high you’ll hit a University of Chicago graduate, and at least decent that […]

tech, startups, internet

Entropy theory.

Several years ago Packy McCormick explained his theory of industry: “Entropy Theory explains industry evolution as a story of ever-increasing chaos and suggests that the most successful businesses are those that use the latest technology to wrangle that chaos, until […]