tech, startups, internet

The Seedpocalypse of 2024.

“Whenever there are “too many” of fundraises of one type, the next round becomes the hardest to raise. In 2024, the Series A Crunch has returned. Software companies that have achieved the previous era’s milestone, $1m or more in ARR, […]

tech, startups, internet

Strategies for an accelerating future.

“One of the things I emphasized to [my students] is that no one really knows what current LLMs are capable of, since most of the tests conducted by AI companies focus mostly on coding and testing benchmarks, not real-world applications. […]

tech, startups, internet

Founder vs investor.

An interview with Elizabeth Zalman and Jerry Neumann. “Together, they have written a somewhat contentious book called Founder vs Investor that lays bare the relationship at the core of most new businesses. They take specific moments in a start-up’s life […]

tech, startups, internet

Dyno Therapeutics: the capsids you need.

A long and detailed post about Dyno Therapeutics, a startup that’s using AI to iterate on capsid (viral protein shell) designs to serve as gene therapy delivery vessels. “In order to understand all of this, I’ve spoken with many of […]

tech, startups, internet

Multimodal LLM innovation continues.

From a team at Meta: “Called Chameleon, the new system is built on an early fusion architecture, and because of that it is able to comingle multiple inputs in ways not possible with most other systems.” ~ learn more

tech, startups, internet

The complete history & strategy of Microsoft.

“The company that put a computer on every desk and in every home. The company that invented the software business model. The company that so thoroughly and completely dominated every conceivable competitor that the United States government intervened and kneecapped […]