under the microscope

Some people resist GLP-1 drugs.

Some people resist GLP-1 drugs. “More GLP-1 was needed to have the same biological effect, meaning they were resistant to GLP-1.” Stanford-led researchers found about 10% of people carry PAM gene variants tied to weaker blood sugar improvements on GLP-1 […]

under the microscope

Magic mushrooms’ remarkable impact on Alzheimer’s patient.

Magic mushrooms’ remarkable impact on Alzheimer’s patient. “Approximately 19 h post-administration, spontaneous autobiographical speech emerged.” A Frontiers in Neuroscience case report describes a woman with advanced Alzheimer’s who showed days to weeks of temporary improvements after a high-dose psilocybin mushroom session, […]

thoughts of food

Dyson strawberries in the supermarket.

Dyson strawberries in the supermarket. “WOW!! First time seeing @Dyson strawberries in the supermarket. Fully nerding out and losing my mind”. Fruit from your favorite vacuum maker! ~ learn more

teaching the kids

How AI killed student writing (and revived it).

How AI killed student writing (and revived it). From NYT: “High school and college teachers are watching students write, in the classroom, in order to protect against the incursion of artificial intelligence.” I, for one, am sad to have missed […]

big ideas

UFOs are the easy belief.

UFOs are the easy belief. “UFOs haven’t been disproven, whereas the blank slate has been disconfirmed nearly 3,000 times.” Jehan Azad argues that some respectable-sounding views (CICO denial, anti-building housing takes, tabula rasa) contradict entire fields more directly than aliens […]

fun facts

Queensbridge.

Queensbridge. I spent a night in Long Island City and walking from the train stop to my hotel, I passed the housing project where one of my favorite artists, Nas, grew up. “From a neighborhood perspective, the album was very […]

fun facts

Europe demands family dynasties.

Europe demands family dynasties. “Many European countries have ‘forced heirship’ laws that require people to leave 50-75% of their estates to their children.” It can even claw back lifetime gifts, making it harder to fund charities and foundations at scale. […]

fun facts

Why Japanese companies do so many different things.

Why Japanese companies do so many different things. Toilet maker Toto is rolling in profits recently. “But Toto’s remarkable year doesn’t have much to do with toilets or bidets.” The piece uses Toto’s pivot into semiconductor components to explain why […]

fun facts

Founders Fund hosts a game of Mafia.

Founders Fund hosts a game of Mafia. “Venture capital firm Founders Fund gathered a group of tech leaders for an evening of Mafia, a murder mystery style parlor game. Players are secretly assigned roles and must use deception and debate […]