Peanut and other allergies may be treatable.

The liver is regularly bombarded with foreign substances, and is home to antigen-presenting cells that train the immune system to tolerate foreign proteins rather than attacking them. Delivering carefully selected protein fragments to the liver helps put a damper on future allergic reactions. Researchers showed that in 2021. In this most recent study, researchers made two upgrades. First, they used an mRNA payload that coded for the protein instead of the actual protein fragment, improving the potential of the platform. Second, they added a sugar molecule to the nanoparticle that binds to antigen-presenting cells to improve the targeting. Mice that were treated showed milder symptoms compared to two other groups. ~ learn more