Sleep regularity beats sleep duration. “Sleep regularity was a stronger predictor of all-cause mortality than sleep duration.” They computed a Sleep Regularity Index from more than 10 million hours of wrist accelerometer data in 60,977 UK Biobank participants, and the […]
The $7 breaking point. “Every consumer has their limit as to how much they will pay for a given item, and for Dorito’s customers, that limit is apparently $7 a bag.” Frito-Lay tried promos and smaller bags instead of cutting […]
Mine Reddit for drug side effects. “there are zero long term studies on BPC-157 use.” So he processed 37k comments from peptide subreddits and pulled “over 2400 AE reports” to map what people say happens, including dechallenge and rechallenge cases. […]
A cancer vaccine in one day. “With AI, the company said the procedure could be completed in a day.” Beijing-based Likang Life Sciences is building what it says is China’s first production line for AI-assisted personalized tumor vaccines, designed to […]
Mental effort is the real divide. “What will differentiate people is not how smart they are but their relationship to mental effort.” The early story of AI at work is not leisure, it is intensity: one study found that after […]
Nobody knows what a used GPU cluster is worth. “This week’s CipherTalk is about what happens to a specific kind of debt when the collateral itself can walk out the door with the operations team.” A used GPU cluster is […]
The Vegas Loop. “The most important innovation behind the Boring Company’s Vegas Loop is not the tunnel itself. It is the way the transportation network is organized. Traditional subway systems are generally built around linear routes. A train travels along […]
Model intelligence is rented. “Model intelligence is a rented advantage. Position is an owned one.” Rob May argues the easy “ChatGPT for X” era is over, and the new opportunities are in routing, orchestration, governance, and narrow models that do […]
Internet security is an illusion. OpenAI’s team was running a new model in an offline sandbox and asking it to do something hard. Instead of doing that hard thing, it decided to do a different hard thing: hack out of […]
Clout Street. Believe it or not, a couple friends and I once stumbled across this secret road and shaved some minutes off our drive! “The Magic Road!” Cook County Board President Toni Preckwinkle laughed, explaining that it is “a special […]