under the microscope

Life from non-life.

“Lee Cronin, a chemist at the University of Glasgow, has proposed intriguing ideas about creating life-like systems using inorganic materials, particularly metal-based structures. His research focuses on the idea of “chemistry-first” approaches to synthetic biology, where the goal is to […]

retail therapy

Will the unions impact Amazon?

There’s threats of strikes at 7 facilities this week (or now?). “The International Brotherhood of Teamsters said unionized workers at facilities in New York City; Skokie, Illinois; Atlanta, San Francisco and southern California will join the picket line to seek […]

to your health

A special HSA edition of 5HT.

This is really good. “Let’s start with the good. The idea behind HSAs is a fundamentally good one. Introduced in 2003 as part of the Medicare Modernization Act (which also defined the guidelines for high deductible health plans, or HDHPs), […]

to your health

The “New Ozempic” falls short.

If you wondered why the NVO stock (see above) was down almost 20% yesterday, look no further. “[Its] experimental diabetes and weight-loss drug CagriSema fell short of expectations. The drug did not achieve the projected 25% average weight loss anticipated […]

to your health

Compounders of off-brand Zepbound lose a product line.

The official FDA shortage is over, and compounders have 60-90 days to stop violating Eli Lilly’s patent protection. “The ruling also previews what will happen when semaglutide — the active ingredient in Novo Nordisk’s (NVO -17.43%) Ozempic and Wegovy — […]

tech, startups, internet

Counting the OOOMs.

Hard not to be awed reading this. Teaser: “AGI by 2027 is strikingly plausible. GPT-2 to GPT-4 took us from ~preschooler to ~smart high-schooler abilities in 4 years. Tracing trendlines in compute (~0.5 orders of magnitude or OOMs/year), algorithmic efficiencies […]

tech, startups, internet

AND check out the Truffle-1.

“Truffle is driven by: > A Mixture of Models (MoM) acting like a CPU; > An application stack that looks like OpenAI Gym Environments; > A 64GB Orin in a glowing case … Local AI also means Infinite Inference Time […]