Automate the entire company. “One of our goals for the year is to automate the entire company. If we all go on vacation at the end of the year, the company should, in many ways, keep running without us.” A […]
People want AI to do things. “The pattern across all 3,000 skills is clear. People don’t want to talk with AI. They want AI to do things for them.” Someone scraped 3,000+ OpenClaw “skills” and treated it like a revealed-preferences […]
Sequencing is a commodity. “Sequencing has become a commodity, like a bag of flour or a gallon of gas — everyone likes cheaper commodities.” A San Diego startup called Element claims its new VITARI device can deliver a whole genome […]
Bundled tasks hide AI gains. “If you’re half as productive at debugging code you didn’t write, or less, the LLM saves you no time at all.” Philip Trammell’s point: automating one slice of a job can break the feedback loop […]
The sports marketing measurement playbook. “L5 is the land of Big Numbers. They look very impressive on slide decks (”450m IMPRESSIONS”). At this level, you are measuring activity, not outcomes.” Avinash Kaushik lays out a 5-level playbook for sports marketing […]
The golden age of vaccine development. “The first vaccine was a lucky accident. Now we can design new vaccines in weeks, atom by atom.” Let’s remember just how lucky we are to have advanced so far with technology: “Stocks of […]
Regulatory roulette at the FDA. “In context, this looks like the regulatory rules of the game are being changed retroactively.” Moderna ran a 43,000 person Phase 3 trial based on FDA guidance, then got hit with a rare Refusal-to-File letter […]
Ring just showed the surveillance future. “a world where biometric identification could be unleashed from consumer devices to identify, track, and locate anything — human, pet, and otherwise.” Amazon pitched “Search Party” as lost-dog reunions, but the ad also made […]
China’s doing more on AI disclosure, but also not that much. “China is essentially the only major country to enact a preemptive, upstream requirement that all AI-generated video be labeled, watermarked, and traceable across the stack.” The piece explains why […]
The final offshoring. “A likely future in which physical labor is commoditized, featuring robot holidays, fashion, futures markets, reshoring (ironically enough), geopolitical instability, sovereign wealth funds, and the bifurcation of everything.” This essay is trying to think all the way […]