tech, startups, internet

Making sense of o3 in public.

“To start, it’s been quite a shock. every conversation i had yesterday revolved around it. it affected my sleep. probably some anomalies in oura data for certain SF neighborhoods last night.” ~ learn more

to your health

The “New Ozempic” falls short.

If you wondered why the NVO stock (see above) was down almost 20% yesterday, look no further. “[Its] experimental diabetes and weight-loss drug CagriSema fell short of expectations. The drug did not achieve the projected 25% average weight loss anticipated […]

tech, startups, internet

The next OS in computing.

“It’s different now. When I manage spreadsheets, I don’t want to manipulate formulas anymore. Instead, I want to instruct the computer as I would explain to a colleague : “run the correlations on these variables to see if anything meaningful […]

to your health

Compounders of off-brand Zepbound lose a product line.

The official FDA shortage is over, and compounders have 60-90 days to stop violating Eli Lilly’s patent protection. “The ruling also previews what will happen when semaglutide — the active ingredient in Novo Nordisk’s (NVO -17.43%) Ozempic and Wegovy — […]

tech, startups, internet

Intelligence arbitrage.

“2010s; build software that solves a problem and sell it to other businesses. 2024; build software that buys businesses. Whether you start with models and use acquisitions for data, compete with PE firms, or create a tech-enabled rollup – the […]

better doing

The not-so-fake citizen.

“I was labeled a “fake citizen” because while I had written an article all about it, I hadn’t actually done anything about it. Fair point, actually.” ~ learn more

tech, startups, internet

Counting the OOOMs.

Hard not to be awed reading this. Teaser: “AGI by 2027 is strikingly plausible. GPT-2 to GPT-4 took us from ~preschooler to ~smart high-schooler abilities in 4 years. Tracing trendlines in compute (~0.5 orders of magnitude or OOMs/year), algorithmic efficiencies […]

fun facts

Racing’s deadliest day.

“How the 1955 Le Mans disaster changed motorsport forever.” I’m not a huge racing enthusiast and didn’t know this story prior to reading. It’s pretty gory. ~ learn more

tech, startups, internet

AND check out the Truffle-1.

“Truffle is driven by: > A Mixture of Models (MoM) acting like a CPU; > An application stack that looks like OpenAI Gym Environments; > A 64GB Orin in a glowing case … Local AI also means Infinite Inference Time […]

fun facts

Encyclopedia of Smell History and Heritage.

I stumbled upon this and am so glad it exists. Today’s link is to an article on Civet. “Unlike musk, ambergris and castoreum, civet had been unknown to the classical Western world. As of its introduction to the European market […]