Pavel Sokolovsky

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Feb 11, 2024

A promising new oral insulin pill.

It works with micro-encapsulation of insulin with a coating that breaks down specifically in the liver and specifically when blood sugar levels are high. Amazing! “The medication that can be taken orally has already been tested on baboons, in which it was found to lower the blood sugar…

Feb 11, 2024

DNA as hardware rather than software.

The team created a nanoscale electromotor, an innovative piece of equipment engineered from DNA. This motor features a turbine design constructed entirely out of DNA strands, arranged to form an axle and three blades, powered by the hydrodynamic flow within a nanopore. ~ learn more

Feb 11, 2024

Decarbonization 2024.

Nat Bullard is a self-described expert on clean energy and climate finance. He puts together this annual presentation on “the state of decarbonization told with climate, capital markets, technology, and sector data.” It’s very detailed and full of interesting data. This 2024 version is 200 slides long. ~ learn more

Feb 11, 2024

How to decarbonize 85% of all industry using today’s technology.

I have not fact-checked this but it did make it through some sort of peer-review. “In a new study published in the journal Joule, the researchers went through a range of different industrial sectors looking at the available options for decarbonization, their emissions reduction potential, and their technology readiness…

Feb 11, 2024

Vitalik on the promise and challenges of crypto + AI.

It’s not all sunshine and rainbows, that’s for sure. ”A particular challenge is: in cryptography, open source is the only way to make something truly secure, but in AI, a model (or even its training data) being open greatly increases its vulnerability to adversarial machine learning attacks. This…

Feb 11, 2024

My best thinking

I was contemplating a minor business problem with a colleague. He sat quietly while a stream of words came out of my mouth. Eventually he commented that we were both thinking, but he was doing so in his head while I was doing so out loud. I think…

Feb 4, 2024

Don’t die: an interview with Bryan Johnson.

“Bryan was disgusting, I was told. “A freak.” A blood sucking, overly-estrogenized bug man. His quest to “live forever” was “demonic,” the seething Twitter trads have long declared. Too online. Dangerous. “Nobody should give this man a platform.” I couldn’t wait to speak with him.” ~ learn more

Feb 4, 2024

How to remove carbon from oceans.

“Like on-land carbon capture technologies, which can extract carbon from our air, marine carbon capture harvests the molecules from seawater or the air above. Carbon causes problems for both: Excess carbon dioxide gas in the atmosphere creates a kind of blanket around our world, trapping more heat as…

Feb 4, 2024

Personal export subsidies.

South Korea established itself as a world class manufacturer in part due to their policy of conditional export subsidies. They’d help their local firms out, but only after they proved overseas customers liked their products. Could this approach work in parenting? “By far the easiest example for personal…