Before CAR-T therapy really picks up steam toward its full life-saving potential, society might see one or more major improvements in its cost or effectiveness. Here’s one: “Traditional CAR-T cells, while effective against liquid cancers, face challenges in solid tumors—the […]
There’s a protein that’s found in the kidney and brain that’s cleverly called KIBRA. “Kauwe, Pareja-Navarro et al. identify a KIBRA-dependent mechanism to repair the plasticity at synapses that is dysregulated in neurons underlying the loss of memory in tauopathy.” […]
It’s hard not to get excited about the cutting edge lab results that the ability to edit DNA has unlocked. “If we give it to aged mice, they rejuvenate. If we give it to young mice, they age slower. No […]
In autoimmune diseases, the body attacks its own cells. That poses a problem because stopping the attack also comes with lowering the body’s immunities against foreign invaders. Some recent understanding of cellular function, supported by clinical trial results, is promising. […]
The team created a nanoscale electromotor, an innovative piece of equipment engineered from DNA. This motor features a turbine design constructed entirely out of DNA strands, arranged to form an axle and three blades, powered by the hydrodynamic flow within […]
It works with micro-encapsulation of insulin with a coating that breaks down specifically in the liver and specifically when blood sugar levels are high. Amazing! “The medication that can be taken orally has already been tested on baboons, in which […]
Interesting research from the University of Toronto, which has a strong legacy and brand in this field. In ironic and stark contrast to the critical take linked above. “In yet another surprise attribute of the new class of obesity drugs, […]
“This breakthrough technology has the potential to revolutionize electronics by eliminating the need for chargers or portable power banks. Devices powered by these nuclear batteries could operate continuously without degradation in capacity or lifespan, unlike traditional Li-ion batteries. Imagine drones […]
“It’s plausible that this not only explains some of the differences we see in how Alzheimer’s progresses, but also signals the need to treat each variant differently, potentially explaining the high failure rate in finding successful treatments up until now.” ~ learn […]
CAR-T therapies have operational scaling challenges (see above). Maybe viral vectors can circumvent those challenges by modifying your T cells while they’re still inside a patient. “Scientists are devising ways to edit the genomes of immune cells without having to […]