under the microscope

Epigenetic edits to cut cholesterol.

“Scientists achieved this effect by changing each animal’s ‘epigenome’, one feature of which is a collection of chemical tags that are bound to DNA and affect gene activity. After the treatment, activity of the targeted gene dropped and remained low […]

under the microscope

Studying flow states with an EEG.

“For the high-experience musicians, the high-flow state was associated with increased activity in auditory and visual areas and reduced activity in key parts of the default-mode network. This suggested that the default-mode network wasn’t contributing much to flow-related idea generation. […]

under the microscope

Epigenetic editing.

So much potential! “An alternative to genome editing can reduce the activity of a gene that affects cholesterol levels without changing the DNA sequence — and does so for an extended period, according to a study in mice.” ~ learn more

under the microscope

NIH nutrition for precision health study.

“The NIH study will involve 10,000 participants in total, some of whom are signing up for intense measures, like monitors that follow them and make sure they don’t eat smuggled food, or special eyeglass attachments to record what they eat.” ~ learn […]

under the microscope

Peter Attia doesn’t like the vegan twin study.

The study, which is also available as a Netflix docuseries, compares results of identical twins assigned either vegan or omnivore diets at random. Attia writes: “While the attempt at controlling for genetics may be admirable, it is at odds with the rest […]

under the microscope

The promise of and problems with phages.

“But for many people, phages aren’t some miraculous elixir. In 2022, researchers published the largest series of case studies of phage therapy for antibiotic-resistant bacterial infections yet. Of the 20 people treated with phages, most with infections related to cystic […]