Weed will now be much less illegal nationally, but with plenty of gray area and contradictory laws. “Trump ordered agencies to begin the formal process of reclassifying cannabis as a drug with medical value and lower abuse potential.” ~ learn more
“Even if approval requirements were relaxed, the underlying need would remain: we still have to learn, through testing in humans, which treatments are effective and which are not.” Clinical development is a costly stage in drug discovery but crucial for determining a therapy’s real-world efficacy. Focusing more on this phase could unlock significant potential in drug innovation. ~ learn more
“Most technical problems are really people problems.” In tackling technical debt, it’s often the human issues—such as outdated habits, unclear requirements, and unrealistic deadlines—that are the root causes. ~ learn more
“When you start seeing every human interaction as a game-theoretic puzzle, you lose access to information that matters.” By reducing relationships to mere transactions, you risk losing out on genuine partnerships and trust. ~ learn more
“AI Agents … massively reduce the labour cost of developing software.” This transformative shift is due to agentic coding, which is streamlining processes that previously required entire teams, reducing project timelines from months to weeks. ~ learn more
“The hacker also shared a list with me of more than 400 TikTok accounts Doublespeed operates. Around 200 of those were actively promoting products on TikTok, mostly without disclosing the posts were ads, according to 404 Media’s review of them.” ~ learn more
Surge AI, with fewer than 100 employees, “surpassed $1 billion in revenue last year, completely bootstrapped—the fastest company in history to reach this milestone.” This is an opinionated interview with Edwin Chen, its founder. ~ learn more
This comes from a fantastic entrepreneur who saw opportunity where everyone else saw risk. “In late 2008 (a full month after I officially left Enova), while banks were imploding, we started buying foreclosed apartments on Chicago’s South and West Sides that no one else wanted. … This is the unglamorous, rejection-filled, wildly rewarding story of Pangea Properties—from boarding up windows ourselves to building a 500+ employee team, a winding road…
Chicago’s data-driven approach suggests “murder can be predicted and we can prevent it from happening.” Recent records forecasted shooting risks accurately, with a shocking 13% of high-risk individuals getting shot within 18 months. ~ learn more
Humans are surprisingly monogamous, ranking “between meerkats and beavers” in a study measuring full sibling rates to infer mating patterns. The research uses genetic data to place humans in a “premier league of monogamy” among mammals. ~ learn more