Pavel Sokolovsky

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under the microscope · Apr 2024

Data is not available upon request.

Oh, my! “Among articles stating that data was available upon request, only 17% shared data upon request. The presence of Data Availability Statements was not associated with higher rates of data sharing(p= .55), indicating a lack of adherence to journals' policies.” ~ learn more

under the microscope · Apr 2024

Things could be better.

Science does not have to be written with dry language and locked away behind inaccessible journals. Adam Mastroianni proves the point by publishing the results of eight studies he conducted. “It goes like this: when people imagine how things could be different, they almost always imagine how things could be better.” ~ learn more

under the microscope · Apr 2024

A critical take on Lantern Bio’s cavity-defying microbes.

In January of 2024 I shared a post about Lantern Bio, who’s “product is a genetically modified bacterium which infects your mouth, outcompetes all the tooth-decay-causing bacteria, and doesn’t cause tooth decay itself”. This data scientist makes the valid point that it’s a little sketchy for folks to talk about this therapy as if it works before any human clinical trial evidence exists. Because, well, lots of things that should…

big ideas · Apr 2024

Bill Gurley speaks from the heart on regulatory capture.

He shares the story of his Washington DC lawyer advising him to get some friends in a room together for a visit from a congressman. He was early in his investing career and the startup he had backed needed support! ~ learn more

profiles of people · Apr 2024

Rags-to-riches of the century: Francis Ngannou.

“His story even starts like a folk tale. Poor even by the standards of his native Cameroon, Francis lived with his grandmother in a one-room, brick-and-dirt house in the village of Batié. From the age of 10, he worked in a local sand mine to supplement their meager income, but still often missed school because of lack of tuition, or was thrown out for being without a notebook and pen.”…

thoughts of food · Apr 2024

3G Capital quietly exited its Kraft Heinz investment last year.

Warren Buffett is supporting the company, or holding the bag — depending on your perspective. “Brazilian private equity firm 3G Capital quietly sold off its 16.1% stake in Kraft Heinz in the fourth quarter, nearly nine years after masterminding the blockbuster merger of Kraft Foods and Heinz with Warren Buffett.” ~ learn more

fun facts · Apr 2024

The rise of the remote husband.

The Economist points out that remote work is not distributed equally. “All over the country, among the well-heeled and well-educated, a new trend appears to be emerging. When the wives head out in the morning, to their offices, classrooms or hospitals, they are waving goodbye to their husbands, who remain at home.” ~ learn more

tech, startups, internet · Apr 2024

The data business, at three resolutions.

“Byron Tau's Means of Control is a fun look at the world of government entities buying data from private companies for law enforcement and intelligence purposes. For anyone who's had experience working with data for hedge funds, or using it to target ads, it's an especially delightful read—it turns out that the same companies providing raw data that offered a better way to track intra-quarter trends in same-store sales were…

under the microscope · Apr 2024

Maybe we can’t actually extend the lifespans of mice?

This is a very provocative analysis. Are there implications for aging science? “Let's start with calorie restriction, shall we? Everyone knows that it slows aging, isn't it? Well, not really. Take a look at the chart below… Each bar represents a genetically distinct strain of mice. A bar above 0 indicates that CR resulted in lifespan extension, and below 0 indicates lifespan shortening. As you can see, the effect was…

better doing · Apr 2024

Avoid blundering: 80% of a winning strategy.

What’s true in amateur chess and tennis is that one can win by avoiding blunders moreso than by winning points. Is it true in startups as well? This author makes the case. ~ learn more