Pavel Sokolovsky

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thoughts of food · Apr 2025

Sea-farmed salmon problems.

“I knew there were problems with salmon reared in captivity at sea, but after witnessing the damage inflicted by life in an ocean pen, I will be voting with my shopping trolley, says Graham Lawton” ~ learn more

under the microscope · Apr 2025

A genome-wide atlas of cell morphology reveals gene functions.

“The new technique lets scientists study the effects of perturbing over 20,000 genes on hundreds of image-based cellular features. Generating data with the method is more than 10 times less expensive than comparable high-dimensional approaches such as high-throughput single-cell RNA sequencing and can be adapted to study a wide variety of cell types. In Nature Methods, the researchers applied PERISCOPE to execute three whole-genome CRISPR screens to create an open-source…

under the microscope · Apr 2025

First time hearing about 4D printing.

“Welcome to 4D printing, a frontier in material and manufacturing science that has been rapidly expanding over the past decade. While 3D printing has captured global attention for its ability to create objects layer by layer, 4D printing adds the element of time.” The application is sofas that self-assemble when you heat them up. ~ learn more

better doing · Apr 2025

The only problem is that it’s all made up.

Recommended reading for AI users, including the Deep Research guy above. “Despite claiming to have looked at every paper published in the Annals in this 75-year period, poking around the pages it looked at suggests it only looked at ~5-6 papers.” ~ learn more

better doing · Apr 2025

How an investor uses Deep Research.

“1. First, I used O1 Pro to build me a prompt for Deep Research to do Deep Research on Deep Research prompting….” ~ learn more

tech, startups, internet · Apr 2025

DeepMind robots playing 1v1 soccer.

Click for video! “Training Robotis OP3, the researchers found they were able to learn movement skills like walking, kicking, and being able to recover from a fall. According to the report, the robots were also able to develop an understanding of the rules of soccer, like anticipating where the ball is going or when to block shots from an opponent.” ~ learn more

tech, startups, internet · Apr 2025

Pulling back the curtain on the magic of Y Combinator.

“But what does the data say about the impact of YC and the success of their bets? We tried to demystify the giant by reviewing the 4,939 YC companies so that startup founders, investors, and others can see what’s really going on—and maybe learn from the successes or trends.” ~ learn more

tech, startups, internet · Apr 2025

Microsoft’s Satya Nadella always impresses.

Ever since I saw him at an Economic Club of Chicago dinner a few years ago, I’ve been a fan. This week he was on a podcast to promote the company’s quantum computing breakthrough. It’s a wonderful interview. He also shared the most reasoned take on AGI that I’ve heard yet, which is to ignore all the noise and focus on getting the world’s economic growth rate up to 10%.…

oh, chicago · Apr 2025

Former Illinois House speaker found guilty.

“Michael Madigan was the last man standing long after other political bosses of his era lost their clout, hung it up or went to prison. … But on Wednesday morning, the former Illinois House speaker — the longest-serving legislative leader in American history — was convicted by a federal jury of bribery, conspiracy and wire fraud, capping a four-month trial.” You may be wondering if this is the end of…