“UConn bioengineers successfully regrew cartilage in a rabbit’s knee, a promising hop toward healing joints in humans, they report in the January 12 issue of Science Translational Medicine.” | learn more
Coinbase founder Brian Armstrong and venture capitalist Blake Byers are starting a new company. “NewLimit will start by deeply interrogating epigenetic drivers of aging and developing products that can regenerate tissues to treat specific patient populations.” | learn more
This paper was recently published in Nature Aging. “Here we review features of senescent cells and strategies for targeting them, including immunologic approaches, as well as key intracellular signaling pathways. Additionally, we survey current senolytic therapies in human trials.” | learn more
Finally, some answers! “A new study suggests that a single genetic mutation helps explain why monkeys have tails, while apes and people do not.” | learn more
“[Startup company] Loyal is holding out the possibility of eventually expanding its business to humans. In the meantime, [founder Celine] Halioua is happy not to be working only with mice. “We have extended the life spans of mice hundreds of times,” […]
Recruiting is hard. “My goal in this essay is to help others make better decisions on a potential hire, business partner, or even life partner as quickly and as accurately as possible. It’s made up of suggested action steps and some […]
I just finished reading a book about the early days of SpaceX. The number of times the company came close to death is remarkable. “SpaceX beats out Jeff Bezos’ Blue Origin and defense contractor Dynetics to be the sole provider […]
“3D printing holds the promise of changing the healthcare industry for the better by offering products such as smarter drugs and hyper-customized prosthetics. …[In] the near future, it might become commonplace for doctors to treat patients with printed organs. In […]
“In this issue of JDST, Alva and colleagues present for the first time, development of a continuous ketone monitor (CKM) tested both in vitro and in humans.” | learn more
This is an excellent and detailed review of the literature regarding intermittent and periodic fasting. “Here, we describe the different fasting methods and their effect on longevity in organisms ranging from yeast to humans, linking them to the major nutrient-sensing signaling […]